STK24 antibody (C-Term)

Catalog No. ABIN360314

The Rabbit Polyclonal anti-STK24 antibody has been validated for IHC (p) and EIA. It is suitable to detect STK24 in samples from Human.

Quick Overview for STK24 antibody (C-Term) (ABIN360314)

Target: STK24 (serine/threonine Kinase 24 (STK24))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK24 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-STK24 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to MST3.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MST3.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for STK24

Target: STK24 (serine/threonine Kinase 24 (STK24))

Alternative Name: STK24 / STK3

Background: The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3, MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2, MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases.Synonyms: MST-3, MST3, Mammalian STE20-like protein kinase 3, STE20-like kinase MST3, Serine/threonine-protein kinase 24

Gene ID: 8428, 9606

UniProt: Q9Y6E0